Research Articles
Neuroinflammation in Neurodegeneration: Mechanisms, Biomarkers, and Therapeutic Strategies
This article provides a comprehensive analysis of the pivotal role inflammatory responses play in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Amyotrophic Lateral Sclerosis.
Mouse Peritonitis Models: A Comprehensive Guide for Evaluating Inflammatory Responses in Preclinical Research
This article provides a systematic overview of mouse peritonitis models, essential tools for studying inflammatory responses, sepsis, and evaluating novel therapeutics.
Comprehensive Flow Cytometry Guide for Macrophage M1/M2 Polarization Analysis
This article provides a complete framework for analyzing macrophage M1/M2 polarization using flow cytometry, tailored for researchers and drug development professionals.
Cytokine Detection Sensitivity: A Comprehensive Comparison of Methods for Biomarker Research and Drug Development
Accurate cytokine quantification is crucial for understanding immune responses, disease mechanisms, and therapeutic efficacy in biomedical research and drug development.
Transcription Factors as Inflammatory Markers: A Comparative Analysis of NF-κB, STAT, and IRF in Disease and Drug Development
This article provides a comprehensive comparative analysis of key inflammatory transcription factors—NF-κB, STAT, and IRF—as biomarkers in biomedical research and therapeutic development.
Beyond CRP: How Novel Omics Markers Are Redefining Inflammation Measurement in Biomedical Research
This article provides a comprehensive analysis for researchers and drug development professionals on the paradigm shift from conventional inflammation biomarkers to novel multi-omics markers.
Oxidative Stress Biomarkers in Chronic Disease: A Comparative Guide for Research and Drug Development
This article provides a comprehensive analysis of oxidative stress biomarkers across major chronic diseases, including cardiovascular disease, diabetes, chronic kidney disease, and neurodegenerative disorders.
Dietary Inflammatory Index and Inflammatory Biomarkers: Correlations with CRP and IL-6 in Research and Clinical Applications
This comprehensive review examines the evidence linking the Dietary Inflammatory Index (DII) with key inflammatory biomarkers CRP and IL-6, addressing both methodological considerations and clinical applications.
Acute Phase Proteins as Biomarkers: A Comparative Analysis of Performance Across Diseases and Modalities
This article provides a comprehensive comparative analysis of the performance of various acute phase proteins (APPs) as biomarkers in clinical and preclinical settings.
Beyond CRP and ESR: Novel Systemic Inflammatory Indices as Next-Generation Biomarkers in Autoimmunity and Oncology
This article provides a comprehensive analysis of novel systemic inflammatory indices, such as the Systemic Immune-Inflammation Index (SII), Pan-Immune-Inflammation Value (PIV), and Neutrophil-Lymphocyte Ratio (NLR), and their advantages over traditional...